What is the primary method by which a horse can become infected with glanders?

Glanders is primarily caused by the bacterium Burkholderia mallei, which can infect horses through various routes. One of the primary methods of infection is through inhalation of contaminated droplets or dust, as the bacteria can be present in respiratory secretions from infected animals. This route is significant because it allows the bacteria to enter the respiratory tract and lead to respiratory disease.

In addition to inhalation, horses can also become infected through breaks in the skin. If an open wound comes into contact with contaminated materials or surfaces, the bacteria can enter the body directly, leading to other forms of infection.

Ingestion is another potential route of infection if the horse consumes contaminated feed or water that has been exposed to the bacteria.

Since all of these routes can contribute to the infection process, the most comprehensive answer encompasses all the methods mentioned. Therefore, recognizing that horses may get glanders through inhalation, breaks in the skin, and ingestion highlights the various ways this disease can affect equine health, making the answer reflect the multifaceted nature of the infection.