Which of the following is NOT true regarding the treatment of Burkholderia Pseudomallei infections?

Long-term oral therapy is not recommended for Burkholderia pseudomallei infections because the treatment guidelines typically involve an initial phase of intravenous therapy followed by a shorter oral maintenance phase. The primary goal is to ensure that the infection is adequately controlled through initial intensive treatment, particularly in severe cases. While some patients may transition to oral therapy after successful IV treatment, the continuation beyond the standard time frame of around 30 days is not typically supported in clinical guidelines.

In severe cases, intravenous therapy is indeed the primary approach, as it allows for immediate and effective administration of antibiotics in a controlled manner. Some cases may not require IV therapy based on the severity and clinical judgment, which aligns with the understanding that not all infections present with severe manifestations that necessitate this intensive treatment. By confining long-term oral therapy to just a part of the overall treatment protocol, the management of Burkholderia infections is tailored for maximum effectiveness.